Especially tell your doctor if you take:. This is not a complete list of Depakote drug interactions. Depakote can cause drowsiness, dizziness, and blurred vision. Do not drive or operate heavy machinery until you know how Depakote affects you. Medicines can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of Depakote, there are no specific foods that you must exclude from your diet when receiving Depakote.
Before taking Depakote, tell your doctor about all of your medical conditions. Especially tell your doctor if you:. Tell your doctor if you are pregnant or plan to become pregnant.
Depakote may harm your unborn baby. The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy. Depakote falls into category D. There is evidence of risk to the unborn baby based on studies in humans or adverse reaction data, but this medication may be given to a pregnant woman if her healthcare provider believes that its benefits to the pregnant woman outweigh any possible risks to her unborn baby.
Depakote is excreted in human milk. Caution should be exercised when Depakote is given to a nursing mother. Depakote sprinkle capsules may be swallowed whole or may be taken by carefully opening the capsule and sprinkling the entire contents on a small amount of soft food such as applesauce or pudding.
The mixture should be swallowed immediately avoid chewing. Do not store for future use. If you miss a dose, take the missed dose as soon as you remember.
If it is almost time for the next dose, skip the missed dose and take your next dose at the regular time. Do not take two doses of Depakote at the same time. Take Depakote exactly as prescribed by your doctor. Follow the directions on your prescription label carefully. The dosage will vary, depending on the indication and response. The recommended starting dose of Depakote for the treatment of mania in bipolar disorder is mg daily.
The dose is increased on the basis of response or desired levels in the blood. The recommended starting dose of Depakote for the prevention of migraine is mg twice daily. The dose may be increased until migraine control is achieved. If you take too much Depakote, call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away.
If Depakote is administed by a healthcare provider in a medical setting, it is unlikely that an overdose will occur. However, if overdose is suspected, seek emergency medical attention. Hepatic failure resulting in fatalities has occurred in patients receiving valproate and its derivatives. Serious side effects and their symptoms can include the following:.
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.
Divalproex sodium oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well. To help avoid interactions, your doctor should manage all of your medications carefully. Taking propofol with divalproex sodium can increase the levels of propofol in your body. If you need to take these drugs together, your doctor will likely decrease your dosage of propofol.
Taking felbamate with divalproex sodium may increase the level of divalproex sodium in your body and increase your risk of side effects. If you take felbamate with divalproex sodium, your doctor may adjust your dosage of divalproex sodium. Taking topiramate with divalproex sodium may increase your risk of high ammonia levels in your blood, or low body temperature hypothermia. Taking aspirin with divalproex sodium may increase the level of divalproex sodium in your body and increase your risk of side effects.
If you take aspirin with divalproex sodium, your doctor may adjust your dosage of divalproex sodium. Taking warfarin with divalproex sodium may increase the levels of warfarin in your body. Your doctor may monitor your INR more often if you need to take divalproex sodium together with warfarin. Taking these drugs with divalproex sodium may decrease the level of divalproex sodium in your body.
This means that it may not work as well to treat your condition. If you have to take a carbapenem antibiotic while taking divalproex sodium, your doctor will monitor your blood levels closely. Examples of these antibiotics include:. Taking zidovudine with divalproex sodium may increase the levels of zidovudine in your body. Your doctor may monitor you more closely for side effects.
Taking some birth control medications with divalproex sodium can lower the amount of divalproex sodium in your body, making it less effective. If you need to use hormonal contraception, such as the pill, your doctor will likely monitor the amount of divalproex sodium in your body. Taking certain mood disorder and seizure drugs with divalproex sodium may increase the levels of these drugs in your body.
Your doctor may adjust your dosage of these medications or monitor you more closely for side effects. Examples of these drugs include:. Taking other mood disorder and seizure drugs with divalproex sodium may decrease the level of divalproex sodium in your body. Your doctor may adjust your dosage of divalproex sodium. Taking rifampin with divalproex sodium may decrease the level of divalproex sodium in your body.
If you take these drugs together, your doctor may adjust your dosage of divalproex sodium. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking. If you develop these symptoms, call or your local emergency services or go to the nearest emergency room.
Taking it again could be fatal cause death. Divalproex sodium can cause drowsiness and dizziness. He cleary stated the dose was mg of Depakote not a whopping 15, mg.
That would almost kill an pound sumo wrestler probably. Do you have proper authorization to be giving medical advice? I am no doctor but it sounds like your body is metabolizing the medicine to fast and that is why it is not staying in your system long enough and your blood levels are low. My son had this problem for a long time and now they have increased his depakote to the maximum dose. His blood levels now are at which seems high but the doctor said it was okay for him. It does take a long time for the depakote to have any effect at all on the liver.
Just to be on the safe side, though I would have your liver enzymes checked. I take mg of Depakote a day which is a lot less then you however I would just keep having your blood work done and your liver enzymes checked.
I agree with Michelle about it taking a long time to do damage to ou liver according to research and my Dr. I hope you get it under control soon! You also have the option to opt-out of these cookies. But opting out of some of these cookies may have an effect on your browsing experience. Necessary Necessary. Necessary cookies are absolutely essential for the website to function properly. This category only includes cookies that ensures basic functionalities and security features of the website.
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